Clinical Trial: Comparative Effectiveness of Cephalexin Plus Trimethoprim-Sulfamethoxazole Versus Cephalexin Alone for Treatment of Uncomplicated Cellulitis: A Randomized Controlled Trial
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چکیده
منابع مشابه
Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial.
BACKGROUND Community-associated methicillin-resistant S. aureus (CA-MRSA) is the most common organism isolated from purulent skin infections. Antibiotics are usually not beneficial for skin abscess, and national guidelines do not recommend CA-MRSA coverage for cellulitis, except purulent cellulitis, which is uncommon. Despite this, antibiotics targeting CA-MRSA are prescribed commonly and incre...
متن کاملEffect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial.
Importance Emergency department visits for skin infections in the United States have increased with the emergence of methicillin-resistant Staphylococcus aureus (MRSA). For cellulitis without purulent drainage, β-hemolytic streptococci are presumed to be the predominant pathogens. It is unknown if antimicrobial regimens possessing in vitro MRSA activity provide improved outcomes compared with t...
متن کاملUse of cephalexin plus trimethoprim/sulfamethoxazole vs cephalexin alone for treatment of uncomplicated cellulitis.
TO THE EDITOR—We read with much interest the article by Pallin et al [1], which presents the data from the double-blind, randomized, placebo-controlled trial that compared the clinical effectiveness of trimethoprim/sulfamethoxazole plus cephalexin vs cephalexin alone in treatment of cellulitis without abscess in the outpatient setting where community-associated methicillin-resistant Staphylococ...
متن کاملA prospective randomized trial of azithromycin versus trimethoprim/sulfamethoxazole in treatment of toxoplasmic retinochoroiditis
PURPOSE To assess the efficacy of oral azithromycin in the treatment of toxoplasmic retinochoroiditis. METHODS A randomized interventional comparative study was conducted on 14 patients with ocular toxoplasmosis who were treated with oral azithromycin and 13 patients who were treated with oral trimethoprim/sulfamethoxazole for 6-12 weeks. The achievement of treatment criteria in the two group...
متن کاملRandomized controlled trial comparing lactulose plus albumin versus lactulose alone for treatment of hepatic encephalopathy.
BACKGROUND Hepatic encephalopathy (HE) is associated with poor prognosis and treatment of HE is primarily directed at the reduction of the blood ammonia levels. The study evaluated the efficacy and safety of albumin plus lactulose versus lactulose alone for treatment of overt HE. METHODS In prospective randomized controlled trial, 120 patients with overt HE were randomized in two groups: grou...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2013
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/cit122